Patients with NMOSD had significantly reduced functional connectivity in the sensorimotor, lateral and left dorsal visual, and executive control networks in the brain compared to healthy people.

Significant gaps remain in our collective ability to treat generalized pustular psoriasis (GPP) flares in a timely and effective manner. Medicine in the mid-20th century was mostly a hit-and-miss ...

For the last 3 years, the PBC Foundation, based in Edinburgh, Scotland, has conducted an annual summit that addresses the challenges and potential remedies for those living with primary biliary ...

New research shows that obese patients had a higher risk of comorbidities and poorer functional status. A simple definition of an epidemic is an illness that becomes unexpectedly widespread within a ...

Thrombosis is a key manifestation of paroxysmal nocturnal hemoglobinuria and can sometimes be life-threatening. Thrombosis is one of the primary manifestations of paroxysmal nocturnal hemoglobinuria ...

Diagnosing systemic vasculitis remains a considerable clinical challenge, as does managing this disease after diagnosis. The general physician should have a working knowledge of vasculitis, including ...

In addition to lower complement levels, patients with ITP had elevated CRP levels compared with healthy controls. Serum complement levels could indicate disease activity in patients with immune ...

Navepegritide was well tolerated, with a safety profile comparable to placebo and low rates of injection site reactions. Navepegritide significantly improved growth outcomes in children with ...

Higher relapse rates were associated with c-ANCA/PR3 positivity and granulomatosis with polyangiitis phenotype. In a retrospective study of patients with antineutrophil cytoplasmic (ANCA)-associated ...

Results of this study demonstrate inconsistent national and international guidelines, thus underscoring the need for robust evidence to define alloimmunization risk and update protocols. Wide ...

An elderly woman was diagnosed with CIDP and was found to have CNS involvement upon autopsy after her death. Chronic inflammatory demyelinating polyneuropathy (CIDP) is a disorder characterized by ...

It is challenging to quantify the theoretical risk for alloimmunization in the first trimester of pregnancy. To date, no study has conducted a specific assessment of the use of Rhesus (Rh) D immune ...