Autoimmune diseases in dermatology
Apr 21, 2018 · The autoimmune cause of this class of blistering skin conditions is confirmed by positive direct immunofluorescence microscopy revealing the deposition of antibodies in the skin. Pemphigus The main types of pemphigus are pemphigus vulgaris , pemphigus foliaceus , and paraneoplastic pemphigus [9].
Skin Conditions A-Z - DermNet
A to Z directory of skin diseases, conditions, and their treatments from DermNet.
Inflammasomes and inflammatory skin diseases - DermNet
What is an inflammatory skin disease? Inflammatory skin diseases are characterised by the activation of the innate and adaptive immune system via the production of pro-inflammatory cytokines [4]. They are classified as autoimmune diseases …
Skin signs of rheumatic disease - DermNet
Many autoimmune connective tissue diseases and vascular conditions in rheumatology have cutaneous manifestations. Skin signs are useful in the diagnosis of rheumatic disease, as they often precede systemic symptoms. They can also act as a prognostic marker and predict systemic involvement. Rheumatic diseases described on this page are:
Diabetic skin disease - DermNet
Diabetic dermopathy is a skin condition characterised by light brown or reddish, oval or round, slightly indented scaly patches most often appearing on the shins. Although these lesions may appear in anyone, particularly after an injury or trauma to the area, they are one of the most common skin problems found in patients with diabetes mellitus.
Skin signs of viral hepatitis - DermNet
Skin signs of chronic viral hepatitis. At least 20% of patients with chronic hepatitis due to HBV or HCV develop skin changes, only a few of which are diagnostic of viral hepatitis. Skin conditions associated with both HBV and HCV. Cryoglobulinaemia types II and III (mixed) — can present with skin signs of cutaneous vasculitis or systemic ...
Blistering skin conditions - DermNet
Diagnosis of chronic blistering diseases often requires skin biopsy for histopathology and direct immunofluorescence. A blood test for specific antibodies ( indirect immunofluorescence ) may also prove helpful in making the diagnosis of an immunobullous disease.
Pustular skin conditions - DermNet
Bachelez H. Pustular psoriasis and related pustular skin diseases. Br J Dermatol. 2018;178(3):614-18. doi:10.1111/bjd.16232 PubMed Filosa A, Filosa G. Neutrophilic dermatoses: a broad spectrum of disease.
Direct immunofluorescence - DermNet
Direct immunofluorescence for the diagnosis of skin diseases. DIF is useful in the diagnosis of suspected autoimmune disease, connective tissue diseases and vasculitis. The staining patterns seen in tissue samples may be specific to a disease entity or they may need to be interpreted with the clinical and histological findings.
Alopecia Areata: Causes, Diagnosis, and Treatment - DermNet
Other autoimmune conditions may be more commonly observed in patients with alopecia areata e.g. thyroid disease, vitiligo, psoriasis, diabetes mellitus, and atopy. How is alopecia areata diagnosed? Alopecia areata is typically diagnosed on clinical features, however additional tests may aid diagnosis. Trichoscopy: