Autoimmune diseases in dermatology
Apr 21, 2018 · An autoimmune screen (eg, anti-nuclear antibodies). Swabs may be taken of a ruptured blister to look for signs of a bacterial infection or herpes virus infection. What is the differential diagnosis for autoimmune blistering skin diseases? Blistering skin rashes associated with systemic illness may present with fever and ‘flu-like' symptoms [14].
Skin signs of rheumatic disease - DermNet
Dermatomyositis (also known as idiopathic inflammatory myopathies) is a heterogeneous group of autoimmune disorders affecting the skin and musculature. Skin signs are critical in diagnosing and classifying dermatomyositis: Amyopathic dermatomyositis — this involves skin changes without muscle or other systemic involvement for more than 6 months.
Skin signs of viral hepatitis - DermNet
Skin signs of chronic viral hepatitis. At least 20% of patients with chronic hepatitis due to HBV or HCV develop skin changes, only a few of which are diagnostic of viral hepatitis. Skin conditions associated with both HBV and HCV. Cryoglobulinaemia types II and III (mixed) — can present with skin signs of cutaneous vasculitis or systemic ...
Lichen planus: Symptoms, Types, and Treatment with Images
Localised skin disease such as herpes zoster; Systemic viral infection, such as hepatitis C (which might modify self-antigens on the surface of basal keratinocytes) Contact allergy, such as to metal fillings in oral lichen planus (rare) and colour photographic developers; Drugs; gold, quinine, quinidine, and others can cause a lichenoid rash.
Urticaria and urticaria-like conditions - DermNet
Autoimmune progesterone dermatitis. Autoimmune progesterone dermatitis is a rare, recurrent and itchy rash affecting women during their childbearing years. Skin lesions appear during the second half of the menstrual cycle and resolve during the menstrual period; Urticaria, urticaria-like weals, eczema-like lesions, blisters and target lesions ...
Autoimmune Progesterone Dermatitis (APD) — DermNet
The type of rash seen in autoimmune progesterone dermatitis can be variable, but the majority of patients present with: Urticaria +/- angioedema and anaphylaxis; Dermatitis. Other reported eruptions include: Non-specific skin changes — morbilliform rash, papules and plaques, vesiculobullous and vesiculopustular lesions, petechiae, and purpura
Blistering skin conditions - DermNet
A skin biopsy may be helpful in making a diagnosis. Acute generalised blistering diseases. Acute febrile neutrophilic dermatosis . Neck, limbs, upper trunk; Pseudovesicular plaques, blisters, pustules, purpura, or ulceration; Disease associations: rheumatoid arthritis, inflammatory bowel disease, autoimmune arthritis, myeloid dysplasia; Biopsy ...
Tumour necrosis factor receptor-associated periodic syndrome
In one large family series, the skin eruption lasted 4-21 days, with a mean of 13 days. Most patients report the rash first appears before the age of 2 years. Other skin rashes described in TRAPS include: Urticaria (hive)-like plaques; Dermal oedema (deeper swelling) Generalised serpiginous (snake-like) patches and plaques
Dermatitis Herpetiformis: Features, Diagnosis, and Treatment
DH presents as intense itch and a symmetrical blistering rash. Vesicles (often 3–5 mm in diameter) or blisters develop on erythematous skin but are often eroded and crusted due to scratching. Distribution is a helpful diagnostic clue; lesions most commonly appear on the scalp, shoulders, buttocks, elbows, and knees.
Sjogren syndrome: Symptoms, Causes, and Treatment - DermNet
Other skin features include dry, rough skin, small vessel vasculitis, and urticarial vasculitis Sjögren syndrome is an autoimmune disease that causes dry eyes and dry mouth as it mainly affects secretory glands of the eyes and mouth.